导师资格：博士生导师

所在教研室/单位： 微生物学教研室

E-mail：[email protected]

研究方向：RNA病毒与宿主相互作用的分子机理研究

个人简介

2009年06月获sexfemboy 微生物学博士学位；2009年07月至今，在 sexfemboy 从事RNA病毒（ZIKV/DENV/HIV-1）与宿主互作的分子机理研究，在宿主因子尤其是脂代谢相关因子调控病毒复制的分子机理等研究领域取得了一系列重要的研究成果，并作为通讯作者（共同通讯作者）和第一作者在Nature Communications、Research、Journal of Virology、Journal of Biological Chemistry、Virology、Retrovirology和BMC Medicine等病毒学权威期刊上发表SCI论文十余篇。近年来，共主持国家自然科学基金4项，广东省自然科学基金3项，广东省省级科技计划项目1项，广东省创新团队子课题1项，高等学校博士点专项基金1项以及中国博士后科学基金1项，并于2016年入选广东省特支计划百千万工程青年拔尖人才。

学术成果

学术论著与教材

  1. Luo XT, Yuan YX, Ma XC, Luo X, Chen JN, Chen CC, Yang XY, Yang JN, Zhu XF, Li MY, Liu Y, Zhang P*, Liu C*. Diacylglycerol O-acyltransferase 2, a Novel Target of Flavivirus NS2B3 Protease, Promotes Zika Virus Replication by Regulating Lipid Droplet Formation. Research. 2024. eCollection.
  2. Huo ZT#, Zhu XF#, Peng QY, Chen CC, Yang XY, Huang CB, Xiang YC, Tian QJ, Liu JY, Liu C*, Zhang P*. LINC08148 promotes the caveola-mediated endocytosis of Zika virus through upregulating transcription of Src. Journal of Virolgoy. 2024. 98(6):e0170523.
  3. Huang YX#, Peng QY#, Tian X#, Chen CC, Zhu XF, Huang CB, Huo ZT, Liu Y, Yang C*, Liu C*, Zhang P*. Nuclear membrane protein SUN2 promotes replication of flaviviruses through modulating cytoskeleton reorganization mediated by NS1. Nature Communications. 2024. 15(1): 296.
  4. Huang CB, Feng F, Shi YX, Li WH, Wang ZQ, Zhu YK, Yuan S, Hu DD, Dai J, Jiang QQ, Zhang R,  C*,  P*. Protein Kinase C Inhibitors Reduce SARS-CoV-2 Replication in Cultured Cells. Microbiology Spectrum. 2022. 10(5):e0105622.
  5. SL#,  QS#, Huang CB, Luo XT, Tian Xu,  C*,  P*. Rottlerin plays an antiviral role at early and late steps of Zika virus infection. . 2022. 37(5): 685-694. 
  6. Lin YX#, Huang CB#, Gao HX,  XB,  QS,  SL,  ZT,  YX, C*,  P*. AMBRA1 promotes dsRNA- and virus-induced apoptosis through interacting with and stabilizing MAVS. Journal of Cell Science. 2022. 135(1): jcs258910.
  7.  Y,  ZT,  QS,  YX,  CC,  YX,  CB,   JF,  C*,  P*. Positive Feedback Loop of Long Noncoding RNA OASL-IT1 and Innate Immune Response Restricts the Replication of Zika Virus in Epithelial A549 Cells. Journal of Innate Immunity. 2021. 13(3):179-193. 
  8. Huang YX#,  QS#,  ZT,  CC,  SL,  XC,  HX,  YX,  XB,  JF,  P*,  C*. Inositol-Requiring Enzyme 1 alpha Promotes Zika Virus Infection through Regulation of Stearoyl Coenzyme A Desaturase 1-Mediated Lipid Metabolism. Journal of Virology. 2020. 94(23):e01229-20. 
  9. Ma XC, Luo X, Zhou SL, Huang YX, Chen CC, Huang CB, Shen L, Zhang P, and Liu C*. Hydroxycarboxylic Acid Receptor 2 Isa Zika Virus Restriction Factor ThatCan Be Induced by Zika VirusInfection Through the IRE1-XBP1Pathway. Frontiers in Cellular and Infection Microbiology. 2020. 9: 480. (
  10. QS#,  SL#,  YX,  ZT,  CC,  X,  JF,  C*,  P*. ANKS4B Restricts Replication of Zika Virus by Downregulating the Autophagy. Frontiers in Microbiology. 2020. 11: 1745.